What it is: The supposed future blockbuster diet drug Qnexa is just the first of several weight loss drugs in final phase testing. All are combinations of existing drugs, making for a faster approval process. Contrave, from Orexigen, is a mix of bupropion, an antidepressant also used to quit smoking, and naltrexone, used for alcoholism and addiction to opiates. Arena pharmaceuticals' Lorcaserin, an appetite suppressant, may finally be approved by the FDA later this year.

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I really need your help as I have always had weight issues and done just about every diet on the planet as a result of which I am not weighing over 110 kg 😭😭😭 I am only 5 ft 6 and I should be about 60 to 65 kg. The motivation is gone, my relationship and understanding of food is ruined and the goal seems impossible - all I want is to wake up in my dream body and then having to maintain it🙏🙏🙏
I used to be slim in my high school days, but since college I have been gaining weight, so much so, that I now look bad, and everyone around is commenting on my weight. I did try some weight loss programs but honestly could not stick to any for too long, none of them showed results anyway, and my problem is not solved a bit. Please, please can anyone suggest me a good way to lose weight? Thanks in advance.
Take lorcaserin, for example. Researchers found that the drug could lead to consistent and sustained loss of more than 5 percent of weight in nearly 40 percent of patients at risk for heart attacks, strokes and death from cardiovascular disease without increasing the likelihood of such events, according to a report published recently in the New England Journal of Medicine.

For decades, the usual doctor spiel is to get 150 minutes a week of moderate exercise. But that hasn’t really translated into any meaningful changes nationally, has it? So here’s where another trendy (uh oh) regimen is gaining popularity, mostly because the growing research is impressive. It’s called High Intensity Interval Training (HIIT), and it basically means you go all out for 30-60 seconds on any activity, getting to maximum exertion, then take a few seconds break, then do another all-out effort, etc etc. You do this 15 minutes tops, twice a week only (typically). Check out an example in the image below from a New York Times article about a 7-minute workout, which I also blogged about in my New York Times column in China. This HIIT routine is great because it requires zero fancy equipment, and you can do it absolutely anywhere. Click here to access the online workout app.

And for those who are in the higher obese categories with BMI over 35 or 40, gastric bypass surgery actually can permanently improve some of that hunger urge. How? Removing the top of the stomach in these surgeries removes the stomach tissues that secrete grehlin; less grehlin = less hunger signals = less eating = weight loss. That’s another important reason why I urge people to consider weight loss surgery.
Although adding an exercise routine to your diet overhaul will help you burn fat more quickly than a dietary intervention alone, one JAMA study found that obese patients who change their diets first and begin exercising six months after their diet change will lose the same amount of weight after 12 months as those participants who eat healthier and exercised over the course of the whole year. In short: don’t put off your weight loss goals just because you don’t want to exercise. Change your diet today, exercise later, and you can still lose weight.
The plan is simple: Commit to two weeks of restricted dieting, then transfer to a sustainable regime. Phase one: Cut out restaurant food, added sugar, eating while watching TV, snacking on anything other than fruits and veggies, and limit meat and dairy. You’re also asked to add four healthy habits, simple tweaks like having a good breakfast every morning.
The nutritionist has slowly led me into a ketogenic diet and within 2 months my PSA has gone from 8 to 6.6 and the latest reading is 6.0. I have gone from 62 kilos to 58 kilos in about 2 weeks and it is fair to say that I do not feel hungry although I have one meal or at most 2 meals a day. I jog almost every day for about 60 minutes keeping my heart rate above 120. My diet bothers everyone else but not me.

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you’re partially describing a ketogenic diet. Instead of getting energy from carbs, you get energy from (good) fat; the intro of sugar into your system is slower and so the pancreas doesn’t have to produce as MUCH insulin; recent British studies show that a pancreas can rejuvenate itself and increase its ability to produce more insulin after given “rehab” time off from constantly producing insulin, too! Amazing.
“We eat with our eyes first and we like to see a full plate. Using smaller plates, bowls, and cups will reduce the amount of food you can serve yourself, while at the same time allow you to fill your dish up and keep you from feeling deprived. For example, an observational study showed that people who used a 9-inch plate versus a 10- or 12-inch plate ate up to 22 percent less!” — Goodman  

Why does this popular plan work? For one thing, it pushes wildly healthy staples to the forefront (think: nuts, vegetables, fruit, olive oil). For another, it's simply delicious, thanks to it's focus on fresh, simply prepared dishes like grilled fish with lemon and whole wheat pita with hummus. Science agrees: One meta-review of 16 studies, found the eating M.O. helped those on it lose an average of 8.5 pounds.
"I eat whatever I want in reasonable portions," says Frankel, whose favorite snacks include navel oranges, baked chips, and pureed vegetable soups. "Some days it's a cookie. No one ever got fat off of one cookie." For those extra-busy days Frankel relies on Skinnygirl Daily On-the-Go Dark Chocolate Multi-Grain Pretzel Bars. They're kosher and vegan while satisfying your sweet tooth. Plus, a pack of two will only set you back 200 calories (also available in banana oatmeal dark chocolate; $9.99 a box at skinnygirldaily.com).
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The average American consumes approximately 15.5 pounds of pasta each year—and most of it is the refined white stuff. Unfortunately, this type of noodle is usually void of fiber and micronutrients. Spaghetti squash, on the other hand, boasts only about 40 calories per cup—more than 75 percent fewer calories than a cup of plain pasta—and is an excellent source of vitamin A and potassium. Make this simple swap to jumpstart your weight loss and you’ll be fitting into your skinny jeans in no time! For more swaps to save you calories, don’t miss these 25 Food Swaps That Cut 2,500 Calories a Week.
Kotsopoulos recommends keeping an apple or some grape tomatoes with you when you're on the go. Dried apricots and apple rings are also purse-friendly and healthier than dried cranberries because they have less sugar. For bar lovers, she recommends Vega Sport Protein Bar in chocolate coconut — it's plant-based, soy free, and contains a hemp protein ($2.99, Whole Foods nationwide).
In addition to its 4 grams of belly-filling fiber, a cup of hearty oatmeal delivers as much protein as an egg. In other words, the popular breakfast food is an excellent weight loss tool. In fact, according to a study in the Annals of Nutrition and Metabolism, scientists found that having oatmeal for breakfast resulted in greater fullness, lower hunger ratings, and fewer calories eaten at the next meal compared with a serving of ready-to-eat sugared corn flakes, even though the calorie counts of the two breakfasts were identical. For an added fiber boost, sprinkle some berries and chia seeds on top of your oatmeal, but be sure to stay away from fattening syrup and sugar.
Many people prefer to stay on the safe side and make weight loss shakes at home. This guarantees that you know exactly what has gone into your shake. When making a homemade weight loss shake, consider the ratio of carbohydrates and protein. A basic recipe includes a banana, ½ cup of yogurt, one serving of protein powder, and a few ice cubes. From there, however, you can add a variety of ingredients to enhance the nutritional value of your shake. Fresh berries, goji berry powder, green tea matcha powder, peanut butter, hemp seeds, coconut oil, spinach, flaxseeds, and pistachios all make excellent additions to a weight loss shake.
Got a serious chocolate craving? This shake will scratch that itch and prevent cravings later in the day when your willpower is weaker, says Amy Shapiro, R.D., C.D.N., and Truvia dietitian. "The avocado adds creaminess and heart-healthy fats and fiber that will keep you full and your skin glowing, too," she says. "The cacao is a powerful antioxidant and the chia seeds provide a dose of omega-3 fatty acids, calcium, protein, and hydration so this smoothie will keep you going all day long." 
Yes, you can eat dark chocolate to lose weight. A study among women with normal weight obesity (or “skinny fat syndrome”) who ate a Mediterranean diet that included two servings of dark chocolate per day showed a substantial reduction in waist size than when on a cocoa-free meal plan. Researchers attribute dark chocolate’s weight loss abilities to flavonoids, heart-healthy compounds in the sweet treat that the scientists at Harvard say can reduce the risk of diabetes, heart disease, and mortality. Like nuts, dark chocolate has also been found to induce satiety. When reaching for chocolate, just make sure you choose a bar with at least 70 percent cacao. Anything less contains more belly-bloating sugar and a significantly reduced flavonoid content.
Coffee jumpstarts your metabolism, making the non-decaf stuff a worthy weight loss ally. According to a study published in the journal Physiology & Behavior, the average metabolic rate of people who drank caffeinated coffee was 16 percent higher than that of those who drank decaf. In addition to caffeinating your coffee, it’s also crucial to keep it black and avoid adding any unhealthy creamers and artificial sweeteners, both of which are enemies of weight loss.
I’m a nutrition graduate (MSc dietetics student) and I’m frankly shocked that this has been allowed to be published. It’s borderline “clean eating”, now proving to be an antecedent to eating disorders and pro Atkins. It also contradicts other articles written by Harvard: https://www.hsph.harvard.edu/nutritionsource/carbohydrates/low-carbohydrate-diets/

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Oatmeal is a breakfast staple but you don't have to eat it as cereal. The high-fiber, super-filling, whole grain is the secret ingredient in this shake from Shawn M Talbott, Ph.D., C.N.S., L.D.N., nutritional biochemist and author. "The combination of fiber and flavonoids in this recipe helps to feed and protect the good bacteria in your gut," he explains. These good bacteria can go on to produce more "feel good" neurotransmitters in the brain which in turn help with mood and weight loss. 


This gluten-free grain can be made in bulk and keeps in the fridge for up to five days. Eat it plain or with just about anything — veggies, a midday salad. Or for breakfast, try Kotsopoulos's favorite meal: A bowl of quinoa with shredded coconut or almond flakes, banana, and cinnamon plus a little vanilla. "Buy the plain kind, just like you would rice," she advises. "Only eating a bowl of white rice is like eating a bowl of sugar, because that's what it turns into." Quinoa is a complete protein source because it has amino acids, as well as stress-busting B vitamins.

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